- British Pharmacopoeia Volume V
- Appendices
- Appendix I A. General Reagents
Bromothymol Blue Solution R1 |
Bromothymol Blue Solution R1
Dissolve 50 mg of bromothymol blue in a mixture of 4 mL of 0.02m sodium hydroxide and 20 mL of ethanol (96%) and dilute to 100 mL with water (pH range, 6.0 to 7.6).
Complies with the following test.
Sensitivity A mixture of 0.3 mL of the solution and 100 mL of carbon dioxide-free water is yellow. Not more than 0.1 mL of 0.02m sodium hydroxide VS is required to change the colour of the solution to blue.