• British Pharmacopoeia Volume V
  • Appendices
  • Appendix I A. General Reagents

Silica Gel for Chromatography, Octadecylsilyl, Base-deactivated
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Silica Gel for Chromatography, Octadecylsilyl, Base-deactivated

A very finely divided (3 μm-10 μm) silica gel, pretreated before the bonding of octadecylsilyl groups by careful washing and hydrolysing most of the superficial siloxane bridges to minimise the interaction with basic components. The particle size is indicated after the name of the reagent in the tests where it is used.

Fine, white or almost white, homogeneous powder, practically insoluble in water and in ethanol (96%).