Desoxycorticosterone Acetate Pellets
» Desoxycorticosterone Acetate Pellets are sterile pellets composed of Desoxycorticosterone Acetate in compressed form, without the presence of any binder, diluent, or excipient. They contain not less than 97.0 percent and not more than 103.0 percent of C23H32O4.
Packaging and storage
Preserve in tight containers suitable for maintaining sterile contents, holding one pellet each.
Solubility in alcohol
A solution of 25 mg of powdered Pellets in 1 mL of alcohol is clear and practically free from insoluble residue.
Identification
B:
Ultraviolet Absorption
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Solution:
10 µg per mL.
Medium:
alcohol.
Absorptivities at 240 nm, calculated on the dried basis, do not differ by more than 3.0%.
Sterility
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Weight variation
Weigh 5 Pellets singly, and calculate the average weight. The average weight is not less than 95% and not more than 105% of the labeled weight of C23H32O4, and each Pellet weighs not less than 90% and not more than 110% of the labeled weight of C23H32O4.
Assay
Standard preparation
Prepare as directed under Assay for Steroids
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Assay preparation
Weigh and finely powder not fewer than 10 Pellets. Weigh accurately about 100 mg of the powder, dissolve it in sufficient alcohol to make 200.0 mL, and mix. Transfer 5.0 mL of this solution to a 250-mL volumetric flask, dilute with alcohol to volume, and mix. Transfer 20.0 mL of this solution to a glass-stoppered, 50-mL conical flask.
Procedure
Proceed as directed for Procedure under Assay for Steroids
![]() ![]() 10C(AU / AS).
Auxiliary Information
Please check for your question in the FAQs before contacting USP.
USP32NF27 Page 2082
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