Sterile Water for Inhalation
noteFor microbiological guidance, see general information chapter Water for Pharmaceutical Purposes
![]() ![]() » Sterile Water for Inhalation is prepared from Water for Injection that is sterilized and suitably packaged. It contains no antimicrobial agents, except where used in humidifiers or other similar devices and where liable to contamination over a period of time, or other added substances.
noteDo not use Sterile Water for Inhalation for parenteral administration or for other sterile compendial dosage forms.
Packaging and storage
Preserve in glass or plastic containers. Glass containers are preferably of Type I or Type II glass.
Labeling
Label it to indicate that it is for inhalation therapy only and that it is not for parenteral administration.
Bacterial endotoxins
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Sterility
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Water conductivity
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Oxidizable substances
To 100 mL add 10 mL of 2 N sulfuric acid, and heat to boiling. For Sterile Water for Inhalation in containers having a fill volume of less than 50 mL, add 0.4 mL of 0.02 M potassium permanganate, and boil for 5 minutes; where the fill volume is 50 mL or more, add 0.2 mL of 0.02 M potassium permanganate, and boil for 5 minutes. If a precipitate forms, cool in an ice bath to room temperature, and pass through a sintered-glass filter: the pink color does not completely disappear.
Auxiliary Information
Please check for your question in the FAQs before contacting USP.
USP32NF27 Page 3871
Pharmacopeial Forum: Volume No. 31(3) Page 802
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