Potassium Bromide Oral Solution, Veterinary
» Potassium Bromide Oral Solution, Veterinary contains an amount of Potassium Bromide equivalent to not less than 151 mg and not more than 185 mg of bromide (Br
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Dissolve an accurately weighed quantity of Potassium Bromide in water. Add Corn Syrup to volume with mixing.
Packaging and storage—
Package in a tight container, and store in a refrigerator.
Labeling—
Label it to indicate that it is to be discarded after 180 days, to state that it is to be kept out of the reach of children, to indicate the nominal content of potassium bromide in the Oral Solution, Veterinary and to state that it is for veterinary use only.
USP Reference standards
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USP Sodium Bromide RS
Beyond-use date:
180 days after the date on which it was compounded.
Assay—
TCA solution—
Dissolve a quantity of trichloroacetic acid in water to obtain a 20% (w/v) solution.
Gold chloride solution—
Dissolve a quantity of gold chloride in water to obtain a 0.5% (w/v) solution.
Blank—
Use water.
Bromide standard stock solution—
Dissolve an accurately weighed quantity of USP Sodium Bromide RS in water to obtain a solution having a known concentration equivalent to about 20 mg of bromide per mL.
Standard preparations—
Prepare four Standard preparation solutions of known concentrations of about 2.0 mg of bromide per mL, 1.0 mg of bromide per mL, 0.5 mg of bromide per mL, and 0.25 mg of bromide per mL by quantitatively diluting the Bromide standard stock solution with the appropriate volumes of water.
Assay preparation—
Dilute Oral Solution, Veterinary quantitatively with water (1:99).
Procedure (see Spectrophotometry and Light Scattering
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in which C is the concentration, in mg per mL, of bromide in the Assay preparation as calculated from the regression line.
Auxiliary Information—
Please check for your question in the FAQs before contacting USP.
USP35–NF30 Page 4358
Pharmacopeial Forum: Volume No. 33(5) Page 936
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