Potassium Iodide
KI 166.00
Potassium iodide
[7681-11-0].
231
(poe tas' ee um eye' oh dide).
KI 166.00
Potassium iodide
[7681-11-0].DEFINITION
Potassium Iodide contains NLT 99.0% and NMT 101.5% of KI, calculated on the dried basis.
IDENTIFICATION
• A. Identification Tests—General, Potassium 191:
Meets the requirements
191:
Meets the requirements
• B. Identification Tests—General, Iodide 191:
Meets the requirements
191:
Meets the requirements
ASSAY
• Procedure
Sample solution:
Dissolve 500 mg of Potassium Iodide in 10 mL of water.
Analysis:
Add 35 mL of hydrochloric acid to the Sample solution, and titrate with 0.05 M potassium iodate VS until the dark brown solution that is produced becomes pale brown. Add 2–3 drops of amaranth TS, and continue the titration slowly until the red color just changes to yellow. Each mL of 0.05 M potassium iodate is equivalent to 16.60 mg of KI.
Acceptance criteria:
99.0%–101.5% on the dried basis
IMPURITIES
Delete the following:
231
Sample solution:
Acceptance criteria:
(Official 1-Dec-2015)
• Iodate
Iodate solution:
Dilute 1 mL of potassium iodate solution (1 in 2500) with water to 100 mL.
Standard solution:
Dissolve 100 mg of Potassium Iodide in ammonia- and carbon dioxide-free water, and add 1 mL of Iodate solution to obtain 10 mL of solution. Transfer to a color-comparison tube, add 1 mL of starch TS and 0.25 mL of 1.0 N sulfuric acid, and mix.
Sample solution:
Dissolve 1.1 g in sufficient ammonia- and carbon dioxide-free water to obtain 10 mL of solution. Transfer to a color-comparison tube, add 1 mL of starch TS and 0.25 mL of 1.0 N sulfuric acid, and mix.
Acceptance criteria:
Any color produced in the Sample solution does not exceed that produced in the Standard solution (NMT 4 µg/g).
• Limit of Nitrate, Nitrite, and Ammonia
Sample solution:
Dissolve 1 g in 5 mL of water.
Analysis:
To the Sample solution contained in a test tube of 40-mL capacity add 5 mL of 1 N sodium hydroxide and 200 mg of aluminum wire. Insert a pledget of purified cotton in the upper portion of the test tube, and place a piece of moistened red litmus paper over the mouth of the tube. Heat the test tube and its contents in a steam bath for 15 min.
Acceptance criteria:
No blue coloration of the paper is discernible.
• Thiosulfate and Barium
Sample solution:
Dissolve 0.5 g in 10 mL of ammonia- and carbon dioxide-free water.
Analysis:
Add 2 drops of 2 N sulfuric acid.
Acceptance criteria:
No turbidity develops within 1 min.
SPECIFIC TESTS
• Alkalinity
Sample solution:
Dissolve 1.0 g of Potassium Iodide in 10 mL of water.
Analysis:
Add 0.1 mL of 0.1 N sulfuric acid and 1 drop of phenolphthalein TS to the Sample solution.
Acceptance criteria:
No color is produced.
• Loss on Drying 731:
Dry a sample at 105
for 4 h: it loses NMT 1.0% of its weight.
731:
Dry a sample at 105 for 4 h: it loses NMT 1.0% of its weight.
ADDITIONAL REQUIREMENTS
• Packaging and Storage:
Preserve in well-closed containers.
Auxiliary Information—
Please check for your question in the FAQs before contacting USP.
| Topic/Question | Contact | Expert Committee |
|---|---|---|
| Monograph | Alan R Potts, PhD
Principal Scientific Liaison (301) 816-8364 |
(SM12010) Monographs - Small Molecules 1 |
USP38–NF33 Page 4946