Title: 2,6-Diaminopurine
CAS Registry Number: 1904-98-9
CAS Name: 1H-Purine-2,6-diamine
Additional Names: 2,6-diamino-9H-purine
Molecular Formula: C5H6N6
Molecular Weight: 150.14
Percent Composition: C 40.00%, H 4.03%, N 55.97%
Literature References: Antagonist of naturally occurring purines: Hitchings, Elion in Metabolic Inhibitors vol. I, R. M. Hochster, J. H. Quastel, Eds. (Academic Press, New York, 1963) pp 216-232. Molecular and electronic structure: Veillard, Pullman, J. Theor. Biol. 4, 37 (1963). First synthesized by Traube, Ber. 37, 4547 (1904) by cyclization of 2,4,5,6-tetraaminopyrimidine. Prepn from guanidine carbonate in 70% yield and refs to earlier prepns: Taylor et al., J. Am. Chem. Soc. 81, 2442 (1959).
Properties: Crystals from ethanol + water, mp 302°. uv max (pH 1.9): 241, 282 nm (log e 3.98, 4.00).
Melting point: mp 302°
Absorption maximum: uv max (pH 1.9): 241, 282 nm (log e 3.98, 4.00) |