Title: 2-Amino-4-picoline
CAS Registry Number: 695-34-1
CAS Name: 4-Methyl-2-pyridinamine
Additional Names: 2-amino-4-methylpyridine; a-amino-g-picoline; 4-methyl-2-aminopyridine
Manufacturers' Codes: W-45
Trademarks: Askensil (Atmos)
Molecular Formula: C6H8N2
Molecular Weight: 108.14
Percent Composition: C 66.64%, H 7.46%, N 25.90%
Literature References: Prepd by heating 4-picoline with sodamide in xylene: Seide, Ber. 57, 791 (1924); 58, 1733 (1925); Räth, ibid. 347. Formulations: von Haxthausen et al., US 2937118 (1960 to Raschig). Pharmacology: von Haxthausen, Arch. Exp. Pathol. Pharmakol. 226, 163; 227, 234 (1955); Marchetti et al., Arch. Int. Pharmacodyn. Ther. 143, 385 (1963).
Properties: Leaflets from petr ether, mp 100-100.5°. bp11 115-117°. Sublimes on slow heating. Freely sol in water, lower alcohols, dimethylformamide, coal tar bases. Slightly sol in petr ether, aliphatic hydrocarbons.
Melting point: mp 100-100.5°
Boiling point: bp11 115-117°
Therap-Cat: Cardiotonic.
Keywords: Analgesic (Non-Narcotic); Cardiotonic. |