Title: 4,4¢-Sulfinyldianiline
CAS Registry Number: 119-59-5
CAS Name: 4,4¢-Sulfinylbisbenzeneamine
Additional Names: di(p-aminophenyl) sulfoxide; 4,4¢-diaminodiphenyl sulfoxide; bis(p-aminophenyl) sulfoxide
Trademarks: Medapsol
Molecular Formula: C12H12N2OS
Molecular Weight: 232.30
Percent Composition: C 62.04%, H 5.21%, N 12.06%, O 6.89%, S 13.80%
Literature References: Analog of dapsone. Prepn: Gazdar, Smiles, J. Chem. Soc. 93, 1835 (1908); GB 509415 (1939 to I. G. Farbenind.), C.A. 34, 3764 (1940); Berti et al., Rev. Bras. Leprol. 20, 104 (1952), C.A. 50, 11520 (1956). In vivo activity vs Mycobacterium leprae: L. Levy, Antimicrob. Agents Chemother. 14, 791 (1978).
Properties: Prisms from alc or water, mp 175°. Slightly sol in water.
Melting point: mp 175°
Therap-Cat: Antibacterial (leprostatic).
Status: This monograph has been retired and is no longer subject to revision or update. |