Title: Acecarbromal
CAS Registry Number: 77-66-7
CAS Name: N-[(Acetylamino)carbonyl]-2-bromo-2-ethylbutanamide
Additional Names: N-acetyl-N-bromodiethylacetylurea; acetylbromodiethylacetylcarbamide; N-acetyl-N¢-a-bromo-a-ethylbutyrylcarbamide; acetylcarbromal
Trademarks: Abasin (Bayer); Sedamyl (3M Pharma)
Molecular Formula: C9H15BrN2O3
Molecular Weight: 279.13
Percent Composition: C 38.73%, H 5.42%, Br 28.63%, N 10.04%, O 17.20%
Literature References: Prepn: DE 327129 (1920 to Bayer), Frdl. 13, 809 (1923). HPLC determn in plasma, urine: M. Höbel, G. Bender, Arch. Toxicol. 37, 307 (1977). GC-MS screening procedure in urine: H. H. Maurer, J. Chromatogr. 530, 307 (1990).
Properties: Crystals, slightly bitter taste, mp 108-109°. Slightly sol in water; freely sol in alcohol, ethyl acetate.
Melting point: mp 108-109°
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Acylic Ureides. |