Title: Alfaprostol
CAS Registry Number: 74176-31-1
CAS Name: (5Z)-7-[(1R,2S,3R,5S)-2-[(3S)-5-Cyclohexyl-3-hydroxy-1-pentynyl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid methyl ester
Additional Names: 18,19,20-trinor-17-cyclohexyl-13,14-didehydro-PGF2a methyl ester
Manufacturers' Codes: Ro-22-9000; K-11941
Trademarks: Alfavet (Roche); Alphacept (SKB)
Molecular Formula: C24H38O5
Molecular Weight: 406.56
Percent Composition: C 70.90%, H 9.42%, O 19.68%
Literature References: Synthetic analog of prostaglandin F2a, q.v. Synthesis: C. Gandolfi et al., DE 2539116; eidem, US 4035415 (1976, 1977 both to Carlo Erba). Efficacy in bovine estrus synchronization: E. Schilling et al., Theriogenology 18, 413 (1982). Treatment of infertility in cows caused by persistent corpus luteum: G. Maffeo et al., Prostaglandins 25, 541 (1983).
Therap-Cat-Vet: Estrus control. |