Title: Benzarone
CAS Registry Number: 1477-19-6
CAS Name: (2-Ethyl-3-benzofuranyl)(4-hydroxyphenyl)methanone
Additional Names: 2-ethyl-3-benzofuranyl p-hydroxyphenyl ketone; 2-ethyl-3-(4-hydroxybenzoyl)benzofuran; 2-ethyl-3-(p-hydroxybenzoyl)coumarone
Manufacturers' Codes: L-2197
Trademarks: Fragivix (Sanofi Winthrop); Vasoc (Lindopharm)
Molecular Formula: C17H14O3
Molecular Weight: 266.29
Percent Composition: C 76.68%, H 5.30%, O 18.02%
Literature References: Prepn: Buu-Hoi, Beaudet, US 3012042 (1961 to Soc. Belge l'Azote Prod. Chim. Marly). Pharmacological studies: Barchewitz et al., Arzneim.-Forsch. 22, 553 (1972). Site of action studies: I. Filipovic, E. Buddecke, ibid. 29, 1578 (1979); L. O. Zwillenberg et al., ibid. 32, 1114 (1982). HPLC determination in serum: H. Vergin, G. Bishop, J. Chromatogr. 183, 383 (1980).
Properties: Crystals, mp 124.3°.
Melting point: mp 124.3°
Therap-Cat: Capillary protectant.
Keywords: Vasoprotectant.
Status: This monograph has been retired and is no longer subject to revision or update. |