Title: Benzodepa
CAS Registry Number: 1980-45-6
CAS Name: [Bis(1-aziridinyl)phosphinyl]carbamic acid phenylmethyl ester
Additional Names: benzyl [bis(1-aziridinyl)phosphinyl]carbamate; benzyl bis(ethylenimido)phosphorourethan; benzcarbimine
Manufacturers' Codes: AB-103; NSC-37096
Trademarks: Dualar (Armour Pharm.)
Molecular Formula: C12H16N3O3P
Molecular Weight: 281.25
Percent Composition: C 51.25%, H 5.73%, N 14.94%, O 17.07%, P 11.01%
Literature References: Prepn: Bardos et al., Nature 183, 399 (1959); Papanastassiou, Bardos, J. Med. Pharm. Chem. 5, 1000 (1962).
Properties: Crystals from benzene + cyclohexane, mp 134-135°. Practically insol in water. Soluble in fat solvents, peanut oil, other oils.
Melting point: mp 134-135°
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Alkylating Agents; Aziridines.
Status: This monograph has been retired and is no longer subject to revision or update. |