Bufeniode
Structural Formula Vector Image
Title: Bufeniode
CAS Registry Number: 22103-14-6
CAS Name: 4-Hydroxy-3,5-diiodo-a-[1-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenemethanol
Additional Names: 1-(4-hydroxy-3,5-diiodophenyl)-2-(1-methyl-3-phenylpropylamino)propanol; diiodobuphenine
Trademarks: Diastal (Bayropharm); Proclival (Houd?
Molecular Formula: C19H23I2NO2
Molecular Weight: 551.20
Percent Composition: C 41.40%, H 4.21%, I 46.05%, N 2.54%, O 5.81%
Literature References: Prepn: J. P. Fourneau, J. M. Delourme, ZA 6800046; eidem, US 3542870 (1968, 1970 both to Lab. Houdé). Metabolism: Veyre et al., C.R. Seances Soc. Biol. Ses Fil. 163, 136 (1969).
Properties: Crystals, mp (slow heating) 185° (dec), mp (fast heating) 212°. LD50 in mice: >600 mg/kg i.p., >2 g/kg orally (Fourneau, Delourme).
Melting point: mp (slow heating) 185° (dec); mp (fast heating) 212°
Toxicity data: LD50 in mice: >600 mg/kg i.p., >2 g/kg orally (Fourneau, Delourme)
Therap-Cat: Antihypertensive; vasodilator (peripheral).
Keywords: Antihypertensive; Vasodilator (Peripheral).

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