Title: Carbostyril
CAS Registry Number: 59-31-4
CAS Name: 2(1H)-Quinolinone
Additional Names: 2-hydroxyquinoline; 2-quinolinol; 2(1H)-quinolone; o-aminocinnamic acid lactam
Molecular Formula: C9H7NO
Molecular Weight: 145.16
Percent Composition: C 74.47%, H 4.86%, N 9.65%, O 11.02%
Literature References: Prepn from quinoline by heating with potassium hydroxide to 225° under anhydr conditions: Tschitschibabin, Ber. 56, 1883 (1923); DE 406208; Chem. Zentralbl. 1925, I, 1536; Frdl. 14, 515.
Properties: Prisms from methanol, mp 199-200°. Sublimes at atmospheric pressure without dec. A monohydrate has been obtained from a satd aq soln. pKb (18°) 8.71. Very sparingly sol in water: One gram dissolves in 950 ml H2O at 22°. Sol in alcohol, ether, dil HCl. Forms easily hydrolyzed Na and K salts.
Melting point: mp 199-200°
pKa: pKb (18°) 8.71
Derivative Type: Compd with 1,3,5-trinitrobenzene
Molecular Formula: (C9H7NO)2.C6H3N3O6
Molecular Weight: 503.42
Percent Composition: C 57.26%, H 3.40%, N 13.91%, O 25.43%
Properties: Yellow needles, mp 178°.
Melting point: mp 178°
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