Title: Chlorquinaldol
CAS Registry Number: 72-80-0
CAS Name: 5,7-Dichloro-2-methyl-8-quinolinol
Additional Names: 5,7-dichloro-8-quinaldinol; 5,7-dichloro-8-hydroxyquinaldine; 5,7-dichloro-2-methyl-8-hydroxyquinoline; hydroxydichloroquinaldine; chloroquinaldol
Trademarks: Gynotherax (Pfizer); Sterosan (Novartis); Steroxin (Novartis)
Molecular Formula: C10H7Cl2NO
Molecular Weight: 228.07
Percent Composition: C 52.66%, H 3.09%, Cl 31.09%, N 6.14%, O 7.02%
Literature References: Prepd by chlorination of 8-hydroxyquinaldine with or without formic acid as solvent: Senn, US 2411670 (1946 to Geigy).
Properties: Yellow needles from alc, mp 114-115° (slight decompn). Medicinal odor. uv max (ethanol): 316 nm (A1%1cm 170); min 280 nm. Practically insol in water. Soly (25°) in ethanol 1.0 g/100 ml of soln; chloroform 5.0 g; acetone 4.0 g; ether 3.0 g; 0.1N NaOH 1.4 g. Also sol in benzene, glacial acetic acid.
Melting point: mp 114-115° (slight decompn)
Absorption maximum: uv max (ethanol): 316 nm (A1%1cm 170)
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial; antifungal.
Keywords: Antiseptic/Disinfectant; Quinolines. |