Title: Clemizole
CAS Registry Number: 442-52-4
CAS Name: 1-[(4-Chlorophenyl)methyl]-2-(1-pyrrolidinylmethyl)-1H-benzimidazole
Additional Names: 1-(p-chlorobenzyl)-2-(1-pyrrolidinylmethyl)benzimidazole; 1-(p-chlorobenzyl)-2-pyrrolidylmethylenebenzimidazole
Molecular Formula: C19H20ClN3
Molecular Weight: 325.84
Percent Composition: C 70.04%, H 6.19%, Cl 10.88%, N 12.90%
Literature References: Prepn: D. Jerchel et al., Ann. 575, 162 (1952); GB 703272; M. Schenck, W. Heinz, US 2689853 (both 1954 to Schering A.G.).
Properties: Crystals from dil alc, mp 167°.
Melting point: mp 167°
Derivative Type: Hydrochloride
CAS Registry Number: 1163-36-6
Trademarks: Allercur (Schering AG)
Molecular Formula: C19H20ClN3.HCl
Molecular Weight: 362.30
Percent Composition: C 62.99%, H 5.84%, Cl 19.57%, N 11.60%
Properties: White microscopic rods from butanol, mp 239-241°. Sol in water.
Melting point: mp 239-241°
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic. |