Title: Clinafloxacin
CAS Registry Number: 105956-97-6
CAS Name: 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Molecular Formula: C17H17ClFN3O3
Molecular Weight: 365.79
Percent Composition: C 55.82%, H 4.68%, Cl 9.69%, F 5.19%, N 11.49%, O 13.12%
Literature References: Fluorinated quinolone antibacterial. Prepn: S. Suzue et al., EP 195316 (1986 to Kyorin). Antibacterial spectrum: M. S. Barrett et al., Diagn. Microbiol. Infect. Dis. 14, 389 (1991); S. M. H. Qadri et al., Chemotherapy (Basel) 38, 92 (1992).
Properties: Milk-white powder from chloroform-methanol-conc. aq. ammonia, mp 253-258° (dec).
Melting point: mp 253-258° (dec)
Derivative Type: Hydrochloride
CAS Registry Number: 105956-99-8
Manufacturers' Codes: AM-1091; CI-960; PD-127391
Molecular Formula: C17H17ClFN3O3.HCl
Molecular Weight: 402.25
Percent Composition: C 50.76%, H 4.51%, Cl 17.63%, F 4.72%, N 10.45%, O 11.93%
Properties: Light yellow prisms from methanol, mp 263-265° (dec).
Melting point: mp 263-265° (dec)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Quinolones and Analogs. |