Title: Danofloxacin
CAS Registry Number: 112398-08-0
CAS Name: 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-3-quinolinecarboxylic acid
Molecular Formula: C19H20FN3O3
Molecular Weight: 357.38
Percent Composition: C 63.85%, H 5.64%, F 5.32%, N 11.76%, O 13.43%
Literature References: Fluorinated quinolone antibacterial. Prepn: M. R. Jefson, P. R. McGuirk, EP 215650; eidem, US 4861779 (1987, 1989 both to Pfizer). See also: F. R. Busch et al., EP 342849 (1989 to Pfizer), C.A. 113, 6177m (1990). Evaluation in treatment of pneumonia in cattle: W. T. R. Grimshaw et al., Dtsch. Tieraerztl. Wochenschr. 97, 529 (1990); C. J. Giles et al., Vet. Rec. 128, 296 (1991). Efficacy in treatment of E. coli diarrhoea in calves: S. J. Sunderland et al., Res. Vet. Sci. 74, 171 (2003).
Properties: mp 268-272°.
Melting point: mp 268-272°
Derivative Type: Methanesulfonate
CAS Registry Number: 119478-55-6
Manufacturers' Codes: CP-76136-27
Trademarks: Advocin (Pfizer)
Molecular Formula: C19H20FN3O3.CH3SO3H
Molecular Weight: 453.48
Percent Composition: C 52.97%, H 5.33%, F 4.19%, N 9.27%, O 21.17%, S 7.07%
Therap-Cat-Vet: Antibacterial. |