Title: Decimemide
CAS Registry Number: 14817-09-5
CAS Name: 4-(Decyloxy)-3,5-dimethoxybenzamide
Manufacturers' Codes: EGYT-1050
Trademarks: Denegyt
Molecular Formula: C19H31NO4
Molecular Weight: 337.45
Percent Composition: C 67.63%, H 9.26%, N 4.15%, O 18.97%
Literature References: Prepn: NL 6605460; E. Kasztreiner et al., US 3432549 (1966, 1969 both to EGYT). Pharmacology: E. Kasztreiner, Magy. Kem. Lapja 27, 370 (1972), C.A. 78, 66697z (1973); I. Kiraly et al., Acta Physiol. Acad. Sci. Hung. 47, 200 (1976). Metabolism study: G. Molnar et al., Acta Pharm. Hung. 48, Suppl., 58 (1978). Toxicity data: E. Usdin, D. H. Efron, Eds., Psychotropic Drugs and Related Compounds (NIH, Washington, D. C., 2nd Ed., 1972) p 377.
Properties: Cryst from methanol, mp 121-122°. LD50 in mice, rats (mg/kg): 2950, 1650 orally (Udsin, Efron).
Melting point: mp 121-122°
Toxicity data: LD50 in mice, rats (mg/kg): 2950, 1650 orally (Udsin, Efron)
Therap-Cat: Anticonvulsant.
Keywords: Anticonvulsant. |