Title: Distigmine Bromide
CAS Registry Number: 15876-67-2
CAS Name: 3,3¢-[1,6-Hexanediylbis[(methylimino)carbonyl]oxy]bis[1-methylpyridinium]dibromide
Additional Names: 3-hydroxy-1-methylpyridinium bromide hexamethylenebis[methylcarbamate]; hexamethylenebis[methylcarbamic acid] ester of 3-hydroxy-1-methylpyridinium bromide; hexamethylenebis[N-methylcarbamic acid ester bromomethylate]; hexamethylenebis[N-methylcarbaminoyl-1-methyl-3-hydroxypyridinium bromide]; hexamarium
Manufacturers' Codes: BC-51
Trademarks: Ubretid (Nycomed)
Molecular Formula: C22H32Br2N4O4
Molecular Weight: 576.32
Percent Composition: C 45.85%, H 5.60%, Br 27.73%, N 9.72%, O 11.10%
Literature References: Prepn: Schmid, US 2789981 (1957 to Oesterr. Stickstoffwerke). Pharmacology: Hertting et al., Arzneim.-Forsch. 18, 479 (1968); Hohenegger, Lindner, Wien. Klin. Wochenschr. 81, 823 (1969). Stability studies: Suzuki, Tanimura, Yakugaku Zasshi 90, 762 (1970).
Properties: Crystals, dec 149°.
Therap-Cat: Cholinesterase inhibitor.
Keywords: Cholinesterase Inhibitor. |