Title: Fluindione
CAS Registry Number: 957-56-2
CAS Name: 2-(4-Fluorophenyl)-1H-indene-1,3(2H)-dione
Additional Names: 2-(p-fluorophenyl)-1,3-indandione
Manufacturers' Codes: LM-123
Trademarks: Previscan (Procter & Gamble)
Molecular Formula: C15H9FO2
Molecular Weight: 240.23
Percent Composition: C 75.00%, H 3.78%, F 7.91%, O 13.32%
Literature References: Prepn: Geiger et al., DE 1130439 (1962 to USV), C.A. 57, 12403a (1962); Molho, Boschetti, FR 1369396 and FR M 6913 (1964, 1969 to LIPHA), C.A. 62, 3988g (1965); 74, 141378u (1971). Alternate syntheses: Shapiro et al., J. Org. Chem. 26, 3580 (1961); Hrnciar, Kovalcik, Chem. Zvesti 16, 200 (1962). Activity and toxicity data: Fontaine et al., Med. Pharmacol. Exp. 17, 497 (1967).
Properties: Crystals from acetic acid, mp 120°. LD50 orally in mice: 240 mg/kg (Fontaine).
Melting point: mp 120°
Toxicity data: LD50 orally in mice: 240 mg/kg (Fontaine)
Therap-Cat: Anticoagulant.
Keywords: Anticoagulant. |