Title: Glyhexamide
CAS Registry Number: 451-71-8
CAS Name: N-[(Cyclohexylamino)carbonyl]-2,3-dihydro-1H-indene-5-sulfonamide
Additional Names: 1-cyclohexyl-3-(5-indanylsulfonyl)urea; 1-cyclohexyl-3-(5-hydrindenylsulfonyl)urea
Manufacturers' Codes: SQ-15860
Trademarks: Subose (BMS)
Molecular Formula: C16H22N2O3S
Molecular Weight: 322.42
Percent Composition: C 59.60%, H 6.88%, N 8.69%, O 14.89%, S 9.95%
Literature References: Prepd from hydrindene-5-sulfonamide and cyclohexyl isocyanate: Hoehn, Breuer, US 3097242 (1963 to Olin Mathieson). Clinical pharmacology: Grinnell et al., Am. J. Med. Sci. 253, 312 (1967).
Properties: Crystals from 70% acetone, mp 153-155°.
Melting point: mp 153-155°
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic; Sulfonylurea Derivatives. |