Title: Guanoxabenz
CAS Registry Number: 24047-25-4
CAS Name: 2-[(2,6-Dichlorophenyl)methylene]-N-hydroxyhydrazinecarboximidamide
Additional Names: 1-[(2,6-dichlorobenzylidene)amino]-3-hydroxyguanidine
Manufacturers' Codes: Compd 43-663
Molecular Formula: C8H8Cl2N4O
Molecular Weight: 247.08
Percent Composition: C 38.89%, H 3.26%, Cl 28.70%, N 22.68%, O 6.48%
Literature References: Prepn: W. J. Houlihan, R. E. Manning, DE 1902449; eidem, US 3591636 (1969, 1971 both to Sandoz). Pharmacological study: J. C. Doxey, A. S. Hersom, Br. J. Pharmacol. 70, 171 (1980).
Derivative Type: Hydrochloride
CAS Registry Number: 23256-40-8
Trademarks: Benzerial (Houd?
Molecular Formula: C8H8Cl2N4O.HCl
Molecular Weight: 283.54
Percent Composition: C 33.89%, H 3.20%, Cl 37.51%, N 19.76%, O 5.64%
Properties: Crystals from ethanol/ether, mp 173-175°.
Melting point: mp 173-175°
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive; Guanidine Derivatives. |