Title: Hementin
CAS Registry Number: 87041-58-5
Literature References: Anticoagulant enzyme from the salivary glands of the South American giant leech Haementeria ghiliarii. Extraction: R. T. Sawyer et al., US 4390630 (1983 to Univ. California, Berkeley). Anticoagulant, fibrinolytic properties: A. Z. Budzynski et al., Proc. Soc. Exp. Biol. Med. 168, 266 (1981). Purification and identification as single polypeptide chain with mol wt approx 120000: S. M. Malinconico et al., J. Lab. Clin. Med. 103, 44 (1984). Proteolytic degradation of fibrinogen by hementin: eidem, ibid. 104, 842 (1984). Protease inhibition: E. H. Murer et al., Thromb. Haemostasis 51, 24 (1984). |