Title: Hydrargaphen
CAS Registry Number: 14235-86-0
CAS Name: [m-[[3,3¢-Methylenebis[2-naphthalenesulfonato]](2-)]]diphenyldimercury
Additional Names: phenylmercuric methylenebis(2-naphthyl-3-sulfonic acid); phenylmercury 2,2¢-dinaphthylmethane-3,3¢-disulphonate; phenylmercuric dinaphthylmethanedisulfonate; methylenedinaphthylenesulfonic acid bisphenylmercuri salt; phenylmercury methylenedinaphthalenesulfonate; bis(phenylmercuri)methylenedinaphthalenesulfonate; phenyl mercuric Fixtan
Trademarks: Conotrane; P.M.F.; Versotrane; Hydraphen; Penotrane (WB Pharm.); Fibrotan; Septotan
Molecular Formula: C33H24Hg2O6S2
Molecular Weight: 981.85
Percent Composition: C 40.37%, H 2.46%, Hg 40.86%, O 9.78%, S 6.53%
Literature References: Prepn: Bywater, Pritchard, GB 584196 and GB 2555114 (1949, 1951 both to Ward, Blenkinsop). Bacteriostatic activity: A. A. Goldberg et al., J. Pharm. Pharmacol. 2, 20 (1950). Review and properties: Goldberg, Manuf. Chem. 22, 182 (1951); Hopf, ibid. 24, 444 (1953).
Properties: Amorphous powder. Practically insol in water but readily goes into colloidal soln in alkali metal dinaphthylmethane disulfonates. The colloidal solns have strong tendency to absorb at interfaces and to form charged hydrated aggregates. LD50 orally in mice: 70 mg/kg (Goldberg).
Toxicity data: LD50 orally in mice: 70 mg/kg (Goldberg)
Use: Bactericide and fungicide for the treatment of wool, hides, leather, textiles, timber and wood-pulp, paints, adhesives.
Therap-Cat: Anti-infective (topical).
Keywords: Antiseptic/Disinfectant; Mercurial compounds.
Status: This monograph has been retired and is no longer subject to revision or update. |