Title: Indospicine
CAS Registry Number: 16377-00-7
CAS Name: (2S)-2,7-Diamino-7-iminoheptanoic acid
Additional Names: L-6-amidinonorleucine; L-2-amino-6-amidinohexanoic acid; L-a-amino-e-amidinocaproic acid
Molecular Formula: C7H15N3O2
Molecular Weight: 173.21
Percent Composition: C 48.54%, H 8.73%, N 24.26%, O 18.47%
Line Formula: H2NC=NH(CH2)4CH(NH2)COOH
Literature References: Teratogenic and hepatotoxic factor found in extracts of Indigofera spicata Forsk (Indogofera endecaphylla Jacq.), Leguminosae. Isoln: Hegarty, Pound, Nature 217, 354 (1968). Isoln, structure and biological studies: eidem, Aust. J. Biol. Sci. 23, 831 (1970). Total synthesis: Culvenor et al., Aust. J. Chem. 24, 371 (1971). Review: Hegarty: Australas. J. Dermatol. 14, 35-38 (1973).
Derivative Type: Monohydrochloride monohydrate
Molecular Formula: C7H15N3O2.HCl.H2O
Molecular Weight: 227.69
Percent Composition: C 36.93%, H 7.97%, N 18.45%, O 21.08%, Cl 15.57%
Properties: Needle-like crystals from aq ethanol, mp 131-134°. [a]D22 +18° (c = 1.1 in 5N HCl).
Melting point: mp 131-134°
Optical Rotation: [a]D22 +18° (c = 1.1 in 5N HCl)
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