Title: Luprostiol
CAS Registry Number: 73523-00-9
CAS Name: (5Z)-7-[(1S,2R,3R,5S)-2-[[(2S)-3-(3-Chlorophenoxy)-2-hydroxypropyl]thio]-3,5-dihydroxycyclopentyl]-5-heptenoic acid
Additional Names: 9a,11a,15-trihydroxy-16-m-chlorophenoxy-13-thia-17,18,19,20-tetranor-5-prostenoic acid; prostianol
Manufacturers' Codes: EMD-34946
Trademarks: Prosolvin (Intervet); Reprodin (Bayer)
Molecular Formula: C21H29ClO6S
Molecular Weight: 444.97
Percent Composition: C 56.68%, H 6.57%, Cl 7.97%, O 21.57%, S 7.21%
Literature References: Analog of prostaglandin F2a, q.v. Prepn: J. Kraemer et al., DE 2513371 (1976 to E. Merck), C.A. 86, 55069k (1977); eidem, US 4309441 (1982 to E. Merck). Luteolytic study in cattle: H. De Vries, H. Feenstra, J. Vet. Pharmacol. Ther. 2, 223 (1979). Estrus cycle regulation: D. Schams, H. Karg, Theriogenology 17, 499 (1982), C.A. 97, 50430p (1982).
Therap-Cat-Vet: Luteolytic. |