Title: Mebeverine
CAS Registry Number: 3625-06-7
CAS Name: 3,4-Dimethoxybenzoic acid 4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]butyl ester
Additional Names: veratric acid 4-[ethyl(p-methoxy-a-methylphenethyl)amino]butyl ester; 3,4-dimethoxybenzoic acid 4-[ethyl(p-methoxy-a-methylphenethyl)amino]butyl ester; 4-[ethyl(p-methoxy-a-methylphenethyl)amino]butyl 3,4-dimethoxybenzoate; 4-[N-[2-(p-methoxyphenyl)-1-methylethyl]-N-ethylamino]butyl 3,4-dimethoxybenzoate
Molecular Formula: C25H35NO5
Molecular Weight: 429.55
Percent Composition: C 69.90%, H 8.21%, N 3.26%, O 18.62%
Literature References: Smooth muscle relaxant. Prepn: BE 609490 C.A. 59, 517b (1963) and T. Kralt et al., DE 1126889; eidem, US 3265577 (1962, 1962, 1966 to N. V. Philips). Pharmacology: G. Bertaccini et al., Farmaco Ed. Sci. 30, 823 (1975).
Derivative Type: Hydrochloride
CAS Registry Number: 2753-45-9
Trademarks: Colofac (Duphar); Duspatalin (Duphar); Duspatal (Duphar)
Molecular Formula: C25H35NO5.HCl
Molecular Weight: 466.01
Percent Composition: C 64.43%, H 7.79%, N 3.01%, O 17.17%, Cl 7.61%
Properties: Crystals from ethyl methyl ketone, mp 105-107° (Ger. patent); also reported as mp 129-131° (Belg. patent).
Melting point: mp 105-107° (Ger. patent); mp 129-131° (Belg. patent)
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic. |