Title: Mefenorex
CAS Registry Number: 17243-57-1
CAS Name: N-(3-Chloropropyl)-a-methylbenzeneethanamine
Additional Names: N-(3-chloropropyl)-a-methylphenethylamine; 1-phenyl-2-(3-chloropropylamino)propane
Molecular Formula: C12H18ClN
Molecular Weight: 211.73
Percent Composition: C 68.07%, H 8.57%, Cl 16.74%, N 6.62%
Literature References: Prepn: Beschke et al., DE 1210873 (1966 to Hoffmann-La Roche), C.A. 64, 19486c (1966). Clinical pharmacology: P. Netter et al., Arzneim.-Forsch. 28, 1310 (1978). GC-MS determn in urine: A. Franceschini et al., J. Chromatogr. 541, 109 (1991). Pharmacokinetics and metabolism: S. Rendic et al., Eur. J. Drug Metab. Pharmacokinet. 19, 107 (1994). Review: J. Engel et al., Drug Alcohol Depend. 17, 229-234 (1986).
Derivative Type: Hydrochloride
CAS Registry Number: 5586-87-8
Manufacturers' Codes: Ro-4-5282
Trademarks: Incital (Fabre Sant?; Pondinil (Roche); Pondinol (Roche)
Molecular Formula: C12H18ClN.HCl
Molecular Weight: 248.19
Percent Composition: C 58.07%, H 7.72%, Cl 28.57%, N 5.64%
Properties: Solid, mp 128-130°.
Melting point: mp 128-130°
NOTE: This is a controlled substance (stimulant): 21 CFR, 1308.14.
Therap-Cat: Anorexic.
Keywords: Anorexic. |