Title: Moroctocog Alfa
Additional Names: (1-742)-(1637-1648)-Blood coagulation factor VIII (human reduced) complex with 1649-2332-blood coagulation factor VIII (human reduced); r-VIII SQ
Trademarks: Refacto (Wyeth)
Literature References: B-domain deleted form of factor VIII produced in Chinese hamster ovary cells by recombinant DNA technology. Prepn: A. Almstedt et al., WO 9109122 (1991 to KabiVitrum); P. Lind et al., Eur. J. Biochem. 232, 19 (1995). Stability of albumin-free preparation: T. Osterberg et al., Pharm. Res. 14, 892 (1997). Clinical pharmacokinetics: K. Fijnvandraat et al., Thromb. Haemostasis 77, 298 (1997). Review of development and clinical experience: E. Berntorp, ibid. 78, 256-260 (1997).
Therap-Cat: Antihemophilic factor.
Keywords: Antihemophilic Factor. |