Title: N-2-Fluorenylacetamide
CAS Registry Number: 53-96-3
CAS Name: N-9H-Fluoren-2-ylacetamide
Additional Names: 2-acetylaminofluorene; AAF; 2-FAA
Molecular Formula: C15H13NO
Molecular Weight: 223.27
Percent Composition: C 80.69%, H 5.87%, N 6.27%, O 7.17%
Literature References: Synthesis: Hayashi, Nakayama, J. Soc. Chem. Ind. Jpn. [Suppl] 36, 127B (1933). Carcinogenicity studies: R. H. Wilson et al., Cancer Res. 1, 595 (1941). Toxicity studies: Haley et al., Proc. Soc. Exp. Biol. Med. 143, 1117 (1973); 146, 648 (1974).
Properties: Crystals from alcohol + water, mp 194°. uv max: 285 nm. Insol in water. Sol in alcohols, glycols, fat solvents.
Melting point: mp 194°
Absorption maximum: uv max: 285 nm
CAUTION: Potential symptoms of overexposure are reduced function of liver, kidneys, bladder and pancreas. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 4. This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-3.
Use: As a positive control to study the carcinogenicity and mutagenicity of aromatic amines. |