Title: N-Methylepinephrine
CAS Registry Number: 554-99-4
CAS Name: 4-[2-(Dimethylamino)-1-hydroxyethyl]-1,2-benzenediol
Additional Names: a-[(dimethylamino)methyl]-3,4-dihydroxybenzyl alcohol; a-(3,4-dihydroxyphenyl)-2-dimethylaminoethanol; a-(3,4-dihydroxyphenyl)-a-hydroxy-b-dimethylaminoethane; dimethylaminomethyl-(3,4-dihydroxyphenyl) carbinol; a-(dimethylaminomethyl)protocatechuyl alcohol; N-methyladrenaline
Molecular Formula: C10H15NO3
Molecular Weight: 197.23
Percent Composition: C 60.90%, H 7.67%, N 7.10%, O 24.34%
Literature References: Prepn and resolution of racemic mixture: Manna, Campiglio, Farmaco Ed. Sci. 14, 317 (1959). Configuration: Manna, Ghislandi, ibid. 19, 377 (1964).
Derivative Type: DL-Form
CAS Registry Number: 6032-14-0
Trademarks: Methadren(e)
Properties: Crystals from alcohol + ethyl acetate, mp 142-143°.
Melting point: mp 142-143°
Derivative Type: D(-)-Form
Properties: Crystals from ethyl acetate, mp 149-150°. [a]D18 -65.1° (c = 1.41 in 0.5N HCl).
Melting point: mp 149-150°
Optical Rotation: [a]D18 -65.1° (c = 1.41 in 0.5N HCl)
Derivative Type: L(+)-Form
Properties: Crystals, mp 149-150°. [a]D18 +62.3° (c = 1.4).
Melting point: mp 149-150°
Optical Rotation: [a]D18 +62.3° (c = 1.4)
Therap-Cat: Adrenergic. |