Title: Nitroakridin 3582
CAS Registry Number: 6035-39-8
CAS Name: 1-Diethylamino-3-[(2,3-dimethoxy-6-nitro-9-acridinyl)amino]-2-propanol
Additional Names: 5-(g-diethylamino-b-hydroxypropyl)amino-2-nitro-7,8-dimethoxyacridine; 9-(3-diethylamino-2-hydroxypropylamino)-6,7-dimethoxy-3-nitroacridine; nitroacridine 3582
Manufacturers' Codes: W-1889
Trademarks: Entozon
Molecular Formula: C22H28N4O5
Molecular Weight: 428.48
Percent Composition: C 61.67%, H 6.59%, N 13.08%, O 18.67%
Literature References: Nitroacridine dye with antimicrobial activity. Prepn: Bockmühl, Fehrle, US 2040070 (1936 to Winthrop); BIOS Final Report No. 766 (1946); Miller, Wagner, J. Org. Chem. 13, 891 (1948); Steck et al., J. Am. Chem. Soc. 79, 4414 (1957). Exptl use for in vitro identification of hypoxic cells: A. C. Begg et al., Br. J. Radiol. 56, 970 (1983).
Properties: Crystals from acetone, mp 168-169°.
Melting point: mp 168-169°
Derivative Type: Dihydrochloride
CAS Registry Number: 73972-50-6
Molecular Formula: C22H28N4O5.2HCl
Molecular Weight: 501.40
Percent Composition: C 52.70%, H 6.03%, N 11.17%, O 15.95%, Cl 14.14%
Properties: Orange crystals, dec 219-220°.
Therap-Cat: Antiseptic.
Status: This monograph has been retired and is no longer subject to revision or update. |