Title: Oxeladin
CAS Registry Number: 468-61-1
CAS Name: a,a-Diethylbenzeneacetic acid 2-[2-(diethylamino)ethoxy]ethyl ester
Additional Names: 2-ethyl-2-phenylbutyric acid 2-(2-diethylaminoethoxy)ethyl ester; 2-(2-diethylaminoethoxy)ethyl a,a-diethylphenylacetate; a,a-diethylphenylacetic acid 2-(2-diethylaminoethoxy)ethyl ester
Molecular Formula: C20H33NO3
Molecular Weight: 335.48
Percent Composition: C 71.60%, H 9.91%, N 4.18%, O 14.31%
Literature References: Prepn: V. Petrow et al., J. Pharm. Pharmacol. 10, 40 (1958); eidem, US 2885404 (1959 to Brit. Drug Houses).
Properties: Yellow oil with an acrid odor and bitter taste. bp0.5 150°; bp0.1 140°. Soluble in dil HCl, ethanol, acetone, ether, toluene; practically insol in water. Stable in acids, unstable in alkalies. Non-hygroscopic.
Boiling point: bp0.5 150°; bp0.1 140°
Derivative Type: Citrate
CAS Registry Number: 52432-72-1
Trademarks: Pectamol (BDH); Pectamon; Paxeladine (Beaufour)
Molecular Formula: C20H33NO3.C6H8O7
Molecular Weight: 527.60
Percent Composition: C 59.19%, H 7.83%, N 2.65%, O 30.32%
Properties: Small needles from ethyl acetate, mp 90-91°. Sol in water.
Melting point: mp 90-91°
Therap-Cat: Antitussive.
Keywords: Antitussive. |