Title: Paroxypropione
CAS Registry Number: 70-70-2
CAS Name: 1-(4-Hydroxyphenyl)-1-propanone
Additional Names: 4¢-hydroxypropiophenone; p-hydroxypropiophenone; paraoxypropiophenone; p-propionylphenol; ethyl p-hydroxyphenyl ketone; P.O.P.
Manufacturers' Codes: B-360; H-365
Trademarks: Profenone; Frenantol (Syntex); Frenohypon; Paroxon; Possipione (Recordati); Hypostat (Herbrand)
Molecular Formula: C9H10O2
Molecular Weight: 150.17
Percent Composition: C 71.98%, H 6.71%, O 21.31%
Literature References: Prepn: Perkin, J. Chem. Soc. 55, 546 (1889); Goldzweig, Kaiser, J. Prakt. Chem. [2] 43, 86 (1891); Cox, J. Am. Chem. Soc. 49, 1028 (1927); Hartung et al., ibid. 53, 4153 (1931); Farinholt, ibid. 55, 3386 (1933); Miller, Hartung, Org. Synth. coll. vol. II (1943) p 543. Derivatives: Buu-Hoi, Rec. Trav. Chim. 68, 759 (1949).
Properties: Needles or prisms from water. mp 149°. One part dissolves in 2896 parts of water at 15°, in 30 parts at 100°. Freely sol in alcohol or ether.
Melting point: mp 149°
Therap-Cat: Pituitary gonadotropic hormone inhibitor.
Keywords: Antigonadotropin. |