Title: Phenbutamide
CAS Registry Number: 3149-00-6
CAS Name: N-[(Butylamino)carbonyl]benzenesulfonamide
Additional Names: 1-butyl-3-(phenylsulfonyl)urea; N-benzenesulfonyl-N¢-butylurea; fenbutamide
Manufacturers' Codes: AL-132; R-131
Trademarks: Diaperos (Merieux); Ipoglon (Diana)
Molecular Formula: C11H16N2O3S
Molecular Weight: 256.32
Percent Composition: C 51.54%, H 6.29%, N 10.93%, O 18.73%, S 12.51%
Line Formula: C6H5SO2NHCONHC4H9
Literature References: Prepn: GB 808071 (1959 to Hoechst), C.A. 53, 14056c (1959); Hokfelt, Joenssen, J. Med. Pharm. Chem. 5, 231 (1962); Brzozowaki, Rocz. Chem. 43, 1761 (1969). Activity studies: Tonse et al., Nature 193, 891 (1962); Khurana et al., Indian J. Med. Res. 55, 1084 (1967).
Properties: Crystals, mp 130-132°.
Melting point: mp 130-132°
Therap-Cat: Antidiabetic.
Keywords: Antidiabetic; Sulfonylurea Derivatives.
Status: This monograph has been retired and is no longer subject to revision or update. |