Title: Piroctone
CAS Registry Number: 50650-76-5
CAS Name: 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone
Molecular Formula: C14H23NO2
Molecular Weight: 237.34
Percent Composition: C 70.85%, H 9.77%, N 5.90%, O 13.48%
Literature References: Pyridone deriv related structurally to ciclopirox, q.v. Prepn: G. Lohaus, W. Dittmar, DE 2, DE 214608 corresp to US 3972888 (1973, 1976 both to Hoechst); eidem, Arzneim.-Forsch. 31, 1311 (1981). Evaluation of efficacy as anti-dandruff agent: E. Futterer, J. Soc. Cosmet. Chem. 32, 327 (1981).
Properties: Crystals, mp 108°.
Melting point: mp 108°
Derivative Type: Ethanolamine salt (1:1)
CAS Registry Number: 68890-66-4
Trademarks: Octopirox (Hoechst)
Molecular Formula: C16H30N2O3
Molecular Weight: 298.42
Percent Composition: C 64.40%, H 10.13%, N 9.39%, O 16.08%
Therap-Cat: Antiseborrheic.
Keywords: Antiseborrheic. |