Title: Prenylamine
CAS Registry Number: 390-64-7
CAS Name: N-(1-Methyl-2-phenylethyl)-g-phenylbenzenepropanamine
Additional Names: N-(3,3-diphenylpropyl)-a-methylphenethylamine; N-(3¢-phenyl-2¢-propyl)-1,1-diphenyl-3-propylamine; 1-phenyl-2-[1¢,1¢-diphenylpropyl-3¢-amino]propane
Manufacturers' Codes: B-436
Trademarks: Elecor (Galenica)
Molecular Formula: C24H27N
Molecular Weight: 329.48
Percent Composition: C 87.49%, H 8.26%, N 4.25%
Literature References: Prepn: G. Ehrhart et al., DE 1100031 C.A. 56, 3413h (1962) and DE 1111642 corresp to US 3152173 (1961, 1961, 1964 all to Hoechst); G. Erhart, Arch. Pharm. 295, 196 (1962). Series of articles on pharmacology and chemistry: Arzneim.-Forsch. 10, 569-588 (1960). Metabolism: M. Volz, ibid. 21, 1320 (1971). Review: J. E. Murphy, J. Int. Med. Res. 1, 204-209 (1973).
Properties: mp 36.5-37.5°.
Melting point: mp 36.5-37.5°
Derivative Type: Lactate
CAS Registry Number: 69-43-2
Trademarks: Angormin (Unifa); Bismetin (Mect); Carditin-Same (Savoma); Coredamin (Meiji); Corontin (Chinoin); Crepasin (Hoei); Daxauten (3M Pharma); Hostaginan (Hoechst); Incoran (ITA); Irrorin; Lactamin (Teisan); Plactamin (Morishita); Reocorin (Farmochimica); Roinin (Mohan); Seccidin (Nippon Kayaku); Sedolatan (Hoechst); Segontin (Hoechst); Synadrin (Hoechst)
Molecular Formula: C27H33NO3
Molecular Weight: 419.56
Percent Composition: C 77.29%, H 7.93%, N 3.34%, O 11.44%
Properties: mp 140-142°. Sparingly sol in water (~0.5%); sol in organic solvents. uv max (chloroform): 260 nm (E1%1cm 170).
Melting point: mp 140-142°
Absorption maximum: uv max (chloroform): 260 nm (E1%1cm 170)
Therap-Cat: Vasodilator (coronary).
Keywords: Calcium Channel Blocker; Arylalkylamines; Vasodilator (Coronary). |