Title: Prodipine
CAS Registry Number: 31314-38-2
CAS Name: 1-(1-Methylethyl)-4,4-diphenylpiperidine
Additional Names: 1-isopropyl-4,4-diphenylpiperidine
Molecular Formula: C20H25N
Molecular Weight: 279.42
Percent Composition: C 85.97%, H 9.02%, N 5.01%
Literature References: CNS stimulating agent with antidepressant and antiparkinson properties. Prepn: H. G. Menge, J. Klosa, DE 1936452; eidem, US 4016280 (1971, 1977 both to Byk Gulden). Evaluation of MAO-inhibitory properties in vivo and in vitro: G. Planz et al., Arzneim.-Forsch. 23, 281 (1973). Effects on 5-hydroxytryptamine uptake in platelets: M. Eltze et al., ibid. 30, 1129 (1980). Comparative study of effects in Parkinson's disease: E. Gründig, F. Gerstenbrand, Wien. Klin. Wochenschr. 92, 868 (1980).
Properties: Oil, bp0.01 117-125°.
Boiling point: bp0.01 117-125°
Derivative Type: Hydrochloride
CAS Registry Number: 31314-39-3
Trademarks: Anthen (Byk Gulden)
Molecular Formula: C20H25N.HCl
Molecular Weight: 315.88
Percent Composition: C 76.05%, H 8.30%, N 4.43%, Cl 11.22%
Properties: Crystals from isopropanol, mp 267°.
Melting point: mp 267°
Therap-Cat: Antiparkinsonian.
Keywords: Antiparkinsonian; Monoamine Oxidase Inhibitor. |