Title: Propallylonal
CAS Registry Number: 545-93-7
CAS Name: 5-(2-Bromo-2-propenyl)-5-(1-methylethyl)-2,4,6(1H,3H,5H)pyrimidinetrione
Additional Names: 5-(2-bromoallyl)-5-isopropylbarbituric acid
Trademarks: Noctal (UCB)
Molecular Formula: C10H13BrN2O3
Molecular Weight: 289.13
Percent Composition: C 41.54%, H 4.53%, Br 27.64%, N 9.69%, O 16.60%
Literature References: Prepn: US 1622129 (1927); cf. Herzog, Arch. Pharm. 263, 216 (1925). Acute toxicity: Maloney, J. Pharmacol. Exp. Ther. 42, 267 (1931).
Properties: Crystals. mp 177-179°. Slightly bitter taste. Slightly sol in water; freely sol in alcohol, glacial acetic acid, acetone, alkalies. Sparingly sol in ether, chloroform, benzene. MLD orally in rabbits: 300-350 mg/kg (Maloney).
Melting point: mp 177-179°
Toxicity data: MLD orally in rabbits: 300-350 mg/kg (Maloney)
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.13.
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives. |