Title: Reposal
CAS Registry Number: 3625-25-0
CAS Name: 5-Bicyclo[3.2.1]oct-2-en-3-yl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
Additional Names: 5-bicyclo[3.2.1]oct-2-en-3-yl-5-ethylbarbituric acid; 5-ethyl-5-(bicyclo[3.2.1]octenyl)barbituric acid
Manufacturers' Codes: WT-161
Trademarks: Reposamal
Molecular Formula: C14H18N2O3
Molecular Weight: 262.30
Percent Composition: C 64.11%, H 6.92%, N 10.68%, O 18.30%
Literature References: Prepn: Taub, US 2808408 (1956 to Calanda Stiftung). Metabolism: Nielsen, Tarding, Acta Pharmacol. Toxicol. 26, 521 (1968). Toxicity: Frey, Arzneim.-Forsch. 12, 389 (1962).
Properties: Needles from isopropanol, mp 213°. pKa 7.4-7.5. LD50 i.p. in mice: 175 mg/kg (Frey).
Melting point: mp 213°
pKa: pKa 7.4-7.5
Toxicity data: LD50 i.p. in mice: 175 mg/kg (Frey)
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.13.
Therap-Cat: Sedative; hypnotic.
Keywords: Sedative/Hypnotic; Barbituric Acid Derivatives.
Status: This monograph has been retired and is no longer subject to revision or update. |