Title: Tuaminoheptane
CAS Registry Number: 123-82-0
CAS Name: 2-Heptanamine
Additional Names: 1-methylhexylamine; 2-aminoheptane
Trademarks: Tuamine (Lilly)
Molecular Formula: C7H17N
Molecular Weight: 115.22
Percent Composition: C 72.97%, H 14.87%, N 12.16%
Line Formula: CH3(CH2)4CH(CH3)NH2
Literature References: a-Adrenergic agonist; topical vasoconstrictor. Prepd by heating 2-bromoheptane on steam bath with alcoholic ammonia in pressure tube: Clarke, J. Am. Chem. Soc. 21, 1027 (1899); by hydrogenation of methyl amyl ketone and ammonia in the presence of Raney nickel: Norton et al., J. Org. Chem. 19, 1054 (1954).
Properties: Volatile liq; d425 0.7600-0.7660; bp760 142-144°; nD25 1.4150-1.4200. Slightly soluble in water. pH of 1% aq soln 11.45. Freely sol in alcohol, ether, petr ether, chloroform, benzene.
Boiling point: bp760 142-144°
Index of refraction: nD25 1.4150-1.4200
Density: d425 0.7600-0.7660
Derivative Type: Hydrochloride
Molecular Formula: C7H17N.HCl
Molecular Weight: 151.68
Percent Composition: C 55.43%, H 11.96%, N 9.23%, Cl 23.37%
Properties: Needles, mp 133°. Soluble in water. pH about 5.4.
Melting point: mp 133°
Derivative Type: Sulfate
CAS Registry Number: 6411-75-2
Trademarks: Heptedrine (Bellon)
Molecular Formula: 2C7H17N.H2SO4
Molecular Weight: 328.51
Percent Composition: C 51.19%, H 11.05%, N 8.53%, S 9.76%, O 19.48%
Properties: Crystals, readily sol in water. The pH of a 1% soln is about 5.4.
Therap-Cat: Nasal decongestant.
Keywords: a-Adrenergic Agonist; Decongestant. |