Title: Uridine 5¢-Diphosphate
CAS Registry Number: 58-98-0
CAS Name: Uridine 5¢-(trihydrogen diphosphate)
Additional Names: UDP; uridine 5¢-pyrophosphate; uridine-5-pyrophosphoric acid
Molecular Formula: C9H14N2O12P2
Molecular Weight: 404.16
Percent Composition: C 26.75%, H 3.49%, N 6.93%, O 47.50%, P 15.33%
Literature References: Can be isolated from calf's liver, thymus, and yeast. The commercial product is derived from yeast. Pentose nucleic acids (isolated from yeast) are digested with rattlesnake venom (freed of 5¢-monoesterase) and the nucleotides are separated by chromatography: Cohn, Volkin, Arch. Biochem. Biophys. 35, 465 (1952); J. Biol. Chem. 203, 319 (1953). For alternate procedures see the refs under Uridine Diphosphate Glucose. Syntheses: Chambers, J. Am. Chem. Soc. 81, 3032 (1959); Moffatt, Khorana, ibid. 83, 649 (1961).
Derivative Type: Lithium salt monohydrate
Molecular Formula: C9H12N2O12P2Li2.H2O
Molecular Weight: 434.04
Percent Composition: C 24.90%, H 3.25%, N 6.45%, O 47.92%, P 14.27%, Li 3.20%
Properties: Crystals, sol in water.
Derivative Type: Sodium salt trihydrate
Molecular Formula: C9H12N2O12P2Na2.3H3O
Molecular Weight: 505.19
Percent Composition: C 21.40%, H 4.19%, N 5.55%, O 47.51%, P 12.26%, Na 9.10%
Properties: Crystals. pKa¢1 6.5; pKa¢2 9.4. uv max (pH 7): 262 nm; (pH 11): 261 nm. Freely sol in water.
pKa: pKa¢1 6.5; pKa¢2 9.4
Absorption maximum: uv max (pH 7): 262 nm; (pH 11): 261 nm
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