Title: Allopregnane-3a,20a-diol
CAS Registry Number: 566-58-5
CAS Name: (3a,5a,20S)-Pregnane-3,20-diol
Additional Names: 5a-pregnane-3a,20a-diol; 3a,20a-dihydroxy-5a-pregnane
Molecular Formula: C21H36O2
Molecular Weight: 320.51
Percent Composition: C 78.69%, H 11.32%, O 9.98%
Literature References: Progesterone metabolite. Isoln from human pregnancy urine: Beall, Biochem. J. 31, 35 (1937); from bulls' urine: Marker et al., J. Am. Chem. Soc. 60, 2931 (1938). Prepn by reduction of 5a-pregn-1-ene-3,20-dione with lithium aluminum hydride: Schütt, Tamm, Helv. Chim. Acta 41, 1751 (1958).
Properties: Crystals from methanol, mp 243-245°. [a]D20 +17° (c = 0.148 in ethanol).
Melting point: mp 243-245°
Optical Rotation: [a]D20 +17° (c = 0.148 in ethanol)
Derivative Type: Diacetate
Molecular Formula: C25H40O4
Molecular Weight: 404.58
Percent Composition: C 74.22%, H 9.97%, O 15.82%
Properties: Crystals, mp 139.5-140.5°. [a]D20 +18° (c = 0.408 in benzene).
Melting point: mp 139.5-140.5°
Optical Rotation: [a]D20 +18° (c = 0.408 in benzene)
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