Title: Arprinocid
CAS Registry Number: 55779-18-5
CAS Name: 9-[(2-Chloro-6-fluorophenyl)methyl]-9H-purin-6-amine
Additional Names: 9-(2-chloro-6-fluorobenzyl)adenine
Manufacturers' Codes: MK-302
Trademarks: Arpocox (Merck & Co.)
Molecular Formula: C12H9ClFN5
Molecular Weight: 277.68
Percent Composition: C 51.90%, H 3.27%, Cl 12.77%, F 6.84%, N 25.22%
Literature References: Prepn: E. P. Lira et al., FR 2128600; eidem, US 3846426 (1972, 1974, both to Int. Minerals and Chem.); G. D. Hartman et al., J. Org. Chem. 43, 960 (1978). Determination in feed: D. W. Fink et al., J. Assoc. Off. Anal. Chem. 61, 1078 (1978); 62, 1 (1979). Evaluation of anticoccidial efficacy: P. Schindler et al., Poult. Sci. 58, 23 (1979); L. R. McDougald, J. K. Johnson, ibid. 72.
Properties: Cryst from methanol/water, mp 245-246°.
Melting point: mp 245-246°
Therap-Cat-Vet: Coccidiostat.
Status: This monograph has been retired and is no longer subject to revision or update. |