Title: Bromuconazole
CAS Registry Number: 116255-48-2
CAS Name: 1-[[4-Bromo-2-(2,4-dichlorophenyl)tetrahydro-2-furanyl]methyl]-1H-1,2,4-triazole
Additional Names: 1-[(2RS,4RS;2RS,4SR)-4-bromo-2-(2,4-dichlorophenyl)tetrahydrofurfuryl]-1H-1,2,4-triazole
Manufacturers' Codes: LS-860263
Trademarks: Granit (Rh>e-Poulenc)
Molecular Formula: C13H12BrCl2N3O
Molecular Weight: 377.06
Percent Composition: C 41.41%, H 3.21%, Br 21.19%, Cl 18.80%, N 11.14%, O 4.24%
Literature References: Ergosterol biosynthesis inhibiting triazole. Prepn: A. Greiner, R. Pepin, EP 258161 (1988 to Rhone Poulenc), C.A. 109, 110440v (1988). Properties and antifungal activity: R. Pepin et al., Brighton Crop Prot. Conf. - Pests Dis. 1990, 439. Effect on fungus ultrastructure: M. Mangin-Peyrard, R. Pepin, Z. Pflanzenkrankh. Pflanzenschutz 103, 142 (1996). Determn by TLC in water: S. Butz, H.-J. Stan, Anal. Chem. 67, 620 (1995); by GC with atomic emission detection in foodstuffs: H.-J. Stan, M. Linkerhägner, J. Chromatogr. A 750, 369 (1996). Field trials in combination with iprodione, q.v.: P. Duvert et al., Agro-Food-Ind. Hi-Tech 7, 34 (1996); in combination with prochloraz, q.v.: eidem, Phytoma 490, 32 (1997).
Properties: White to off-white odorless powder, mp 84°. Moderate to high soly in organic solvents; soly in water 50 mg/l. Vapor pressure (25°): 0.3 ´ 10-7 mm Hg. LD50 orally in rats, mice: 365, 1151 mg/kg; LD50 dermally in rats: >2000 mg/kg; LD50 by inhalation in rabbits: >5 mg/l; LC50(96 hr) in rainbow trout, bluegill sunfish (mg/l): 1.7, 3.1 (Pepin).
Melting point: mp 84°
Toxicity data: LD50 orally in rats, mice: 365, 1151 mg/kg; LD50 dermally in rats: >2000 mg/kg; LD50 by inhalation in rabbits: >5 mg/l; LC50(96 hr) in rainbow trout, bluegill sunfish (mg/l): 1.7, 3.1 (Pepin)
Use: Agricultural fungicide. |