Title: Chalcomycin
CAS Registry Number: 20283-48-1
Molecular Formula: C35H56O14
Molecular Weight: 700.81
Percent Composition: C 59.98%, H 8.05%, O 31.96%
Literature References: Antibiotic substance produced from Streptomyces bikiniensis NRRL 2737: Frohardt et al., DE 1109835 (1960 to Parke, Davis). Structure: Woo et al., J. Am. Chem. Soc. 86, 2726 (1964). Review: Jordan, "Chalcomycin" in Antibiotics I, D. Gottlieb, P. Shaw, Eds. (Springer-Verlag, New York, 1967) pp 446-450.
Properties: Crystals from butanol, mp 121-123°. [a]D27 -43.5° (ethanol). uv max: 218 nm (e 22770). Sol in ethyl acetate, methanol, ethanol, benzene, toluene, chloroform; sparingly sol in carbon tetrachloride, ether, water. Practically insol in petr ether.
Melting point: mp 121-123°
Optical Rotation: [a]D27 -43.5° (ethanol)
Absorption maximum: uv max: 218 nm (e 22770) |