Title: Chlorproethazine
CAS Registry Number: 84-01-5
CAS Name: 2-Chloro-N,N-diethyl-10H-phenothiazine-10-propanamine
Additional Names: 2-chloro-10-(3-diethylaminopropyl)phenothiazine; 3-chloro-10-(3-diethylaminopropyl)phenothiazine
Manufacturers' Codes: RP-4909
Molecular Formula: C19H23ClN2S
Molecular Weight: 346.92
Percent Composition: C 65.78%, H 6.68%, Cl 10.22%, N 8.07%, S 9.24%
Literature References: Prepn: Buisson et al., US 2769002 (1956 to Rhône-Poulenc).
Derivative Type: Hydrochloride
CAS Registry Number: 4611-02-3
Trademarks: Neuriplege (G¢rier)
Molecular Formula: C19H23ClN2S.HCl
Molecular Weight: 383.38
Percent Composition: C 59.52%, H 6.31%, Cl 18.49%, N 7.31%, S 8.36%
Properties: Crystals, mp 178°. (Free base bp1 225-240°). Sensitive to light. Soly in water about 1.0 g/60 ml, ethanol about 1.0 g/300 ml, chloroform 1.0 g/5 ml. Practically insol in acetone, ether, benzene. pH of 1% aq soln 4.8.
Melting point: mp 178°
Boiling point: Free base bp1 225-240°
Therap-Cat: Topical analgesic. |