Title: Defosfamide
CAS Registry Number: 3733-81-1
CAS Name: N,N-Bis(2-chloroethyl)-N¢-(3-hydroxypropyl)phosphorodiamidic acid 2-chloroethyl ester
Additional Names: 2-chloroethyl N,N-bis(2-chloroethyl)-N¢-(3-hydroxypropyl)phosphorodiamidate; N,N,O-tris(2-chloroethyl)-N¢-(3-hydroxypropyl)phosphoric acid diamide; desmofosfamide
Manufacturers' Codes: B-612
Molecular Formula: C9H20Cl3N2O3P
Molecular Weight: 341.60
Percent Composition: C 31.64%, H 5.90%, Cl 31.14%, N 8.20%, O 14.05%, P 9.07%
Literature References: Prepn: Arnold et al, DE 1061780 (1959 to Asta-Werke).
Properties: Oily liquid. Sp gr 1.3675. Practically insol in water. Sol in organic solvents.
Therap-Cat: Antineoplastic.
Status: This monograph has been retired and is no longer subject to revision or update. |